After lung cancer, prostate cancer is the second most frequent tumor among Spanish men. As stated in the Meeting 'What's new on Prostate Cancer?, it is estimated that by 2015 the incidence of prostate cancer in Spain will be approximately 16,000 cases. On the other hand, it is observed that each time affects younger men, specifically, around 50 years. "Although the diagnostic peak is between 60 and 80 years, a second peak has been identified that begins to stand out in the young male population," explained Dr. Almudena Zapatero, specialist in Radiation Oncology at the University Hospital of La Princesa ( Madrid).

"The prevalence is increasing, probably due to the influence of environmental factors and lifestyles, as well as the development of screening programs in primary care centers and specialties and the increase of social awareness," he said. Dr. Zapatero. "Every time there is a clearer awareness in our environment about the value of PSA in blood, a test to detect the presence of prostate cancer, but we are still far from what happens in the United States," he added. However, he added, "what is clear is the need to identify the most at risk patients, mainly first-degree relatives, such as siblings and children, to undergo early screening."

On the other hand, Dr. Zapatero recalled that 85-90% of cases are diagnosed in non-metastatic stages and the curability index is high (above 75%). "It is also a long evolution, even in cases of relapse, so we can say that we are facing a chronic disease," he said. Since the end of the 1980s, mortality has stabilized or declined in countries where the PSA test and curative treatments have been widely applied. This is consistent with a possible moderate effect of curative treatments for prostate cancer diagnosed early, along with better treatments for more advanced cancers. This specialist clarified that "the risk of relapses in localized disease depends on the associated risk factors, thus, in a patient with precocious disease of low risk, the 10-year survival is superior to 90%, and in a patient with cancer of High-risk localized prostate treated with the best RT technology at high doses and androgen deprivation is greater than 75%. "

In terms of prevention, although today there is no clear consensus or definitive results on preventive treatments, "undoubtedly a healthy life with regular physical exercise and a balanced diet rich in vitamins A, E and D are basic recommendations," Dr. Zapatero.

Prostate Cancer in Younger Men (November 2019).