Pregnant women exposed to bisphenol A (BPA) -A chemical that is used in the manufacture of plastics and epoxy resins can suffer oxidative stress, which increases the risk that your future baby will develop diabetes or long-term cardiac disease, according to research published in the journal of the American Society of Endocrinology.
Vasantha Padmanabhan, lead author of the study, explained that her work provides the first evidence that exposure to BPA during pregnancy can induce a specific type of oxidative stress, known as nitrosative stress, in the pregnant woman and her child. Oxidative stress is related to the insulin resistance and the inflammation, factors that in turn are associated with the propensity to develop diabetes and other metabolic problems, and with cardiovascular diseases.
Oxidative stress is related to insulin resistance and inflammation, which in turn are associated with the risk of developing diabetes and cardiovascular diseases
The researchers analyzed blood samples from 24 mothers and their children to see the impact of BPA exposure on their health. Thus, during the first trimester of pregnancy, blood was taken from pregnant women and separated into two groups, one with lower levels of BPA, and the other with levels that were higher. After delivery, blood samples were obtained from the umbilical cords to measure the amount of chemical byproducts caused by oxidative stress.
The results of the analyzes showed that women exposed to higher levels of BPA and their babies had signs of oxidative stress due to overexposure to free radicals derived from nitric oxide, and had a large amount of byproducts generated by this type in their blood. of oxidative damage. In Padmanabhan's opinion, the conclusions of the work indicate that pregnant women should reduce their exposure to BPA as much as possible.