The consumption of Artificial sweeteners It has already been associated with an increased risk of developing diabetes and obesity, and now a new study not only confirms this association, but has also proven - in mice and in cell cultures - that the abuse of these products causes a deterioration of blood vessels.

The research, whose results have been presented at the Experimental Biology 2018 meeting, has focused on comparing two types of sugars, glucose and fructose, with the sweeteners without calories Aspartame and acesulfame potassium, which are commonly used to make food and beverages. Although both sugar and artificial sweeteners impaired the functions of blood vessels, these damages occurred in different ways.

Acesulfame potassium accumulates in the body, and when it reaches high concentrations causes damage to blood vessels

In both cases changes in the levels of fats, amino acids and other chemicals in the blood of the mice were observed, but the artificial sweeteners seemed to alter the way in which the body processes fats and obtains energy. It was also found that the potassium acesulfame it accumulated slowly in the body, and when it reached high concentrations in the blood damage to the cells lining the blood vessels were more serious.

Alterations in the metabolism of fat and energy

Brian Hoffman, associate professor in the Department of Biomedical Engineering at Marquette University and Medical College of Wisconsin in Milwaukee, and director of the research, explained that replacing glucose and fructose with artificial non-caloric sweeteners resulted in negative changes in the metabolism of fat and energy. And he added that our body can cope with a moderate consumption of sugars, but abuse of these products for a long period of time causes health problems.

These vascular changes, according to the authors of this work, "may be important during the onset and progression of diabetes and obesity."

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