An international group of researchers has developed a new therapy that combines several drugs that could eliminate more than 99% of bacteria in patients with tuberculosis (TB) in a period of only two weeks, and that could also be used as a treatment against to multiresistant tuberculosis cases that do not respond to the drugs currently used.
The results of the trial in which the therapy was tested showed that it eliminated more than 99% of the bacteria of patients with tuberculosis
The drugs included in this treatment are PA-824, moxifloxacin -which is an antibiotic that is in development-, and pyrazinamide, and were tested in a phase II trial with the participation of 85 patients with tuberculosis during a couple of weeks The results of this study, which has published 'The Lancet', showed that these combined drugs were able to eliminate more than 99% of the bacteria of these patients.
An additional advantage of the new therapy is that it does not interfere with the administration of antiretroviral drugs used in the treatment of AIDS, and this is a breakthrough because currently tuberculosis is the most frequent cause of death in people infected with AIDS. The hiv.
Data from the World Health Organization (WHO) indicate that every year nine million new cases of tuberculosis are detected worldwide, and that the disease kills almost one and a half million people in the same period of time. weather. In addition, this infection is still present in countries where it was believed that it had been practically eradicated.