When the future baby dies inside the uterus of his mother after week 14 of pregnancy, which is known as intrauterine death of the fetus, in more than 50% of cases the reasons are unknown why the death has occurred .
The autopsy can not always detect the causes of death, but a new genetic test that is performed first to the deceased fetus and later to their parents, has discovered that up to 8% of these deaths can be due to two genetic malformations related to pathologies. cardiac diseases, one of which is Brugada syndrome -Named after by the Spanish doctor of the same name who identified him.
The test reveals that up to 8% of cases of intrauterine death of the fetus due to unknown causes are due to genetic abnormalities associated with two heart diseases.
The new genetic analysis is the result of a study that was presented at the Annual Meeting of the European Society of Human Genetics, whose authors decided to carry out an investigation taking into account that between 10 and 15 percent of children deaths due to sudden death are carriers of genetic alterations related to Brugada syndrome or long QT, two hereditary diseases characterized by an irregular heart rhythm.
Researchers explain that performing the test on deceased fetuses and detecting any of these anomalies, would help to diagnose them also in the mother, which would allow to administer an appropriate treatment - usually beta-blockers - and prevent the next pregnancy can also end with the death of the fetus. For this reason, Alice Ghidoni, from the University of Pavia in Italy and one of the authors of the study, recommends that this test be established as a routine test whenever there is intrauterine death of the fetus without known cause.