People with a genetic predisposition can develop precancerous cells by suffering a bacterial infection in the gastrointestinal tissue, according to a study from the Children's Hospital of Massachusetts and the Harvard Medical School in Boston (United States).

A study, whose results can be found in the journal Proceedings of the National Academy of Sciences (PNAS), shows that infection by bacteria Pseudomonas aeruginosa It can cause gastrointestinal cancer.

For the trial, the scientists infected fruit flies, which were genetically altered with a very virulent strain of the bacterium.Pseudomonas aeruginosathat, in addition, infects human beings.

The researchers discovered that infection by the pathogenic agent (microorganism capable of producing an infectious disease) had a synergistic effect, that is, that several movements, actions or events are associated or coordinated in order to fulfill a certain function.

Therefore, the aberrant cells (which have an abnormal behavior) persisted after infection by the bacteria P. Aeruginosa eradicated.

This research may help in the fight against cancer, developing new methods and tools to obtain a better diagnosis, according to the authors of the study.

New Options for Gastrointestinal Cancer Therapies (November 2019).